By John D. Pickard, Nejat Akalan, Vladimir Benes, Concezio Di Rocco, Vinko V. Dolenc, J. Lobo Antunes, Johannes Schramm, Marc Sindou
The ambition of all winning editorial forums has been to supply a chance for mature scholarship and mirrored image, now not limited through man made limits on house. The sequence presents a extraordinary acocunt of development during the last 35 years, either with reference to advances, specified descriptions of normal operative methods and in-depth studies of tested wisdom. the current quantity is a brand new enterprise and identification considering a unmarried subject particularly - low-grade gliomas. It contains a multidisciplinary process that are meant to entice either skilled neurosurgeons and younger neurosurgeons in education alike.
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Additional info for Advances and Technical Standards in Neurosurgery, Vol. 35: Low-Grade Gliomas
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Karyotyping and comparative genomic hybridization analyses revealed trisomy 7 or gains of chromosome 7q as a common genomic imbalance, which is detectable in up to 50% of diffuse astrocytomas. Further chromosomal aberrations comprise losses on 22q, 19q, 13q, 10p, 6 and the sex chromosomes as well as gains on 5p, 9 and 19p . In contrast to oligodendrogliomas (see below), combined losses on 1p and 19q are rare in diffuse astrocytomas. Pleomorphic xantoastrocytoma (WHO grade II) Epidemiological, histological and immunohistochemical features Pleomorphic xanthoastrocytoma (PXA) accounts for less than 1% of all astrocytic neoplasms.
51 51 51 51 51 52 53 53 56 57 Abstract The term ‘‘low-grade glioma’’ refers to a heterogeneous group of slowly growing glial tumors corresponding histologically to World Health Organization (WHO) grade I or II. This group includes astrocytic, oligodendroglial, oligoastrocytic and ependymal tumor entities, most of which preferentially manifest in children and young adults. Depending on histological type and WHO grade, growth patterns of low-grade gliomas are quite variable, with some tumors diffusely inﬁltrating the surrounding central nervous system tissue and others showing well demarcated growth.
Advances and Technical Standards in Neurosurgery, Vol. 35: Low-Grade Gliomas by John D. Pickard, Nejat Akalan, Vladimir Benes, Concezio Di Rocco, Vinko V. Dolenc, J. Lobo Antunes, Johannes Schramm, Marc Sindou