By Bhanu P. Jena
This is often the 1st publication to hide the historical past, constitution, and alertness of atomic strength microscopy in cellphone biology. awarded within the transparent, well-illustrated sort of the Methods in mobilephone Biology sequence, it introduces the AFM to its readers and permits them to faucet the facility and scope of this know-how to extra their very own study. a pragmatic laboratory advisor to be used of the atomic strength and photonic strength microscopes, it presents up-to-date expertise and techniques in strength spectroscopy. it's also a accomplished and easy-to-follow useful laboratory consultant for using the AFM and PFM in organic study.
Read or Download Atomic Force Microscopy in Cell Biology, Volume 68 PDF
Best methodology & statistics books
A textual content on advanced research, treating very important effects from assorted angles, offering a distinct point of view on complicated research: that of a geometrical functionality theorist and a generally proficient and released analyst. beneficial properties adequate fabric for a complete direction in advanced research, with easy fabric and upper-level path fabric.
Earth Sciences examines the explorers and scientists who enterprise into the unknown frontiers of this medical box and the unforeseen issues they typically discover. Describing the evolution of major themes in Earth sciences, this e-book explains the issues researchers are at the moment investigating in addition to the tools they've got constructed to unravel them.
Chemical information research, with points of metrology in chemistry and chemometrics, is an evolving self-discipline the place new and higher methods of doing issues are consistently being constructed. This ebook makes info research basic by way of demystifying the language and each time attainable giving unambiguous methods of doing issues.
Enzymes are vital instruments in recombinant DNA know-how and genetic engineering. This publication not just presents details for enzymologists, yet does so in a fashion that would additionally relief nonenymologists in making right use of those biocatalysts of their learn. The Enzymology Primer for Recombinant DNA expertise contains info no longer frequently present in the short descriptions given in so much books on recombinant DNA method and gene cloning.
Extra info for Atomic Force Microscopy in Cell Biology, Volume 68
And H¨orber, J. K. H. (1999). Microsc. Res. Tech. 44, 327. Furness, D. , Hackney, C. , and Benos, D. J. (1996). Hearing Res. 93, 136. 30 J. K. Heinrich Horber ¨ G¨obel, H. , H¨orber, J. K. , and H¨ansch, T. W. (1992). Ultramicroscopy 42–44, 1260. , and H¨orber, J. K. H. (1997). Ultramicroscopy 69, 129. , H¨orber, J. K. , and Binnig, G. (1991). J. Vac. Sci. Technol. B9, 1210. Hackney, D. D. (1995). Nature 377, 448. , and Brenner, H. (1965). “Low Reynolds Number Hydrodynamics,” Prentice Hall, Englewood Cliffs, NJ.
56, 930. Corey, D. , and Hudspeth, A. J. (1983). J. Neurosci. 3, 962. Crevel, I. -T. , and Cross, R. A. (1996). J. Mol. Biol. 257, 66. , and H¨orber, J. K. H. (1998). Cell Biol. Intern. 21, 707. , H¨orber, J. K. , and Stelzer, E. H. K. (1996). Appl. Phys. Lett. 69, 446. , Moy, V. , and Gaub, H. E. (1994). Science 264, 415. , H¨orber, J. K. , and Stelzer, E. H. K. (1997). J. Struct. Biol. 119, 202. , Stelzer, E. H. , and H¨orber, J. K. H. (1998). Appl. Phys. A 66, S75. , and H¨orber, J. K. H. (1999).
A major problem is that the high-resolution structural data are obtained on an ensemble of molecules in a rigid state and cannot resolve the dynamic of intermediate states required for the kinesin motility. Furthermore, the molecules used for structural analysis are truncated constructs missing the stalk. On the other hand, for in vitro motility assays, full-length constructs of the motors are used in an environment which is rather different from that of a protein crystal. 1. Local Probe Techniques 25 Fig.
Atomic Force Microscopy in Cell Biology, Volume 68 by Bhanu P. Jena