Atomic Force Microscopy in Cell Biology, Volume 68 by Bhanu P. Jena PDF

By Bhanu P. Jena

ISBN-10: 0125441711

ISBN-13: 9780125441711

This is often the 1st publication to hide the historical past, constitution, and alertness of atomic strength microscopy in cellphone biology. awarded within the transparent, well-illustrated sort of the Methods in mobilephone Biology sequence, it introduces the AFM to its readers and permits them to faucet the facility and scope of this know-how to extra their very own study. a pragmatic laboratory advisor to be used of the atomic strength and photonic strength microscopes, it presents up-to-date expertise and techniques in strength spectroscopy. it's also a accomplished and easy-to-follow useful laboratory consultant for using the AFM and PFM in organic study.

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And H¨orber, J. K. H. (1999). Microsc. Res. Tech. 44, 327. Furness, D. , Hackney, C. , and Benos, D. J. (1996). Hearing Res. 93, 136. 30 J. K. Heinrich Horber ¨ G¨obel, H. , H¨orber, J. K. , and H¨ansch, T. W. (1992). Ultramicroscopy 42–44, 1260. , and H¨orber, J. K. H. (1997). Ultramicroscopy 69, 129. , H¨orber, J. K. , and Binnig, G. (1991). J. Vac. Sci. Technol. B9, 1210. Hackney, D. D. (1995). Nature 377, 448. , and Brenner, H. (1965). “Low Reynolds Number Hydrodynamics,” Prentice Hall, Englewood Cliffs, NJ.

56, 930. Corey, D. , and Hudspeth, A. J. (1983). J. Neurosci. 3, 962. Crevel, I. -T. , and Cross, R. A. (1996). J. Mol. Biol. 257, 66. , and H¨orber, J. K. H. (1998). Cell Biol. Intern. 21, 707. , H¨orber, J. K. , and Stelzer, E. H. K. (1996). Appl. Phys. Lett. 69, 446. , Moy, V. , and Gaub, H. E. (1994). Science 264, 415. , H¨orber, J. K. , and Stelzer, E. H. K. (1997). J. Struct. Biol. 119, 202. , Stelzer, E. H. , and H¨orber, J. K. H. (1998). Appl. Phys. A 66, S75. , and H¨orber, J. K. H. (1999).

A major problem is that the high-resolution structural data are obtained on an ensemble of molecules in a rigid state and cannot resolve the dynamic of intermediate states required for the kinesin motility. Furthermore, the molecules used for structural analysis are truncated constructs missing the stalk. On the other hand, for in vitro motility assays, full-length constructs of the motors are used in an environment which is rather different from that of a protein crystal. 1. Local Probe Techniques 25 Fig.

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Atomic Force Microscopy in Cell Biology, Volume 68 by Bhanu P. Jena


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